The Global Fund is a 21stcentury partnership organization designed to accelerate the end of AIDS, tuberculosis and malaria as epidemics.

Founded in 2002, the Fund raises and invests nearly $4 billion a year to support programs run by local experts in countries and communities most in need. As of September 2015, the Global Fund had disbursed $27 billion to support programs for HIV, tuberculosis and malaria.


As the world’s largest public health financier, the Global Fund provides support to countries in response to the three diseases, but does not implement programs on the ground. Therefore, partnerships are vital to the Fund’s success. Included in these partnerships are relationships with key U.S. bilateral global health programs: the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), the U.S. President’s Malaria Initiative (PMI) and the U.S. Agency for International Development’s (USAID) tuberculosis programs.

The Global Fund works closely with these programs to scale up and leverage investments; build in-country capacity; and jointly plan for procurement and supply chain management, with more details in the diagram below.

Working with the U.S. and other governments, civil society, the private sector and people affected by the three diseases, the Global Fund strives for maximum impact. This partnership has enabled the Global Fund to support programs that have saved more than 17 million lives since 2002. Current projections show that more than 2 million lives are being saved each year, and the Global Fund partnership is on track to have supported countries in saving more than 22 million lives by the end of 2016. Additionally, the Global Fund’s 2015 Results Report found a decline of one-third fewer deaths from HIV/AIDS, tuberculosis and malaria since 2002 in Global Fund-supported countries. The report also indicates that: 8.1 million people are receiving antiretroviral treatment for HIV through Global Fund-supported programs, a 22 percent increase since last year; 548 million mosquito nets have been distributed to protect against malaria; and 13.2 million people have received treatment and care for tuberculosis.

Though its primary function is financing, the Global Fund maintains a connection with its grants by conducting an ongoing country-level dialogue through Country Coordinating Mechanisms (CCMs). The CCM is a forum made up of representatives from both the public and private sectors, including governments, multilateral and bilateral agencies, non-governmental organizations, private businesses and representatives from affected populations. CCMs are central to the Global Fund’s commitment to collaboration, local ownership and participatory decision-making. They also provide a natural forum for engagement with key bilateral partners such as PEPFAR, PMI and USAID. The CCMs develop and submit grant proposals to the Global Fund based on priority needs at the national level. Following grant approval, CCMs oversee progress during implementation and allow for further coordination between the Global Fund and its bilateral partners.

“If there is one crystal clear fact we have learned in the past decade of fighting these deadly diseases, it is that we can only win by coordinating our actions. The sum of our efforts far exceeds what we can do individually.”
– Mark Dybul, Global Fund Executive Director


Read the full report here.

Working with PEPFAR

The Global Fund and PEPFAR bring unique complementary resources to the table. Together, the Global Fund and PEPFAR are working to create a long-term, sustainable response to the HIV/AIDS pandemic.

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Working with PMI

The Global Fund and PMI — the two leading donors in the fight against malaria — have, since the start, coordinated their efforts on the group in implementing countries to maximize their impact on the global malaria burden.

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Working with USAID

The Global Fund and USAID work to identify gaps in national tuberculosis strategies and, by coordinating resources and activities, help to fill those gaps.

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